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omicverse

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@omicverse

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97Public Repos
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72Published Skills

Building interoperable open-source tools for next-generation omics data analysis.

Skills Distribution
DomainData Systems...Single-Cell Genomics (40%)Spatial Transcript.. (25%)Bulk RNA-Seq Analy.. (20%)Microbiome & Metab.. (15%)

Agent Skills by omicverse

Showing 72 vetted skills indexed across 3 GitHub repositories.

omicverseomicverse
13

omicverse-reference-label-transfer

Transfer cell-type labels from reference to query AnnData objects.

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omicverseomicverse
13

omicverse-bulk-celltype-deconvolution

Infer cell-type fractions from bulk RNA-seq using a paired single-cell reference.

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Advanced
omicverseomicverse
13

omicverse-single-cell-cellrank-fate

Maps RNA velocity to CellRank terminal-state probabilities for AnnData workflows.

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omicverseomicverse
13

omicverse-single-cell-cellvote-consensus

Build consensus cell-type labels for AnnData objects with conflicting single-cell annotations.

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omicverseomicverse
13

omicverse-single-cell-cellphonedb-communication

Analyze single-cell ligand-receptor communication from annotated AnnData objects.

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omicverseomicverse
13

omicverse-microbiome-da-comparison

Compare microbiome differential-abundance results across Wilcoxon, pyDESeq2, and ANCOM-BC on AnnData cohorts.

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omicverseomicverse
13

omicverse-single-cell-monocle2-trajectory

Fit Monocle2-style trajectories on AnnData to derive pseudotime and branch-dependent gene programs.

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omicverseomicverse
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omicverse-single-cell-liana-communication

Infer ligand-receptor communication from annotated single-cell AnnData objects.

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omicverseomicverse
13

omicverse-single-cell-scenic

Convert single-cell SCENIC analysis into a reusable regulon workflow for AnnData datasets.

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omicverseomicverse
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omicverse-single-cell-cnmf-program-discovery

Discover gene programs in single-cell AnnData datasets with OmicVerse cNMF.

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omicverseomicverse
13

omicverse-single-cell-cellmatch-ontology

Map free-text cell-type labels to canonical Cell Ontology terms.

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omicverseomicverse
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omicverse-cross-modal-celltype-transfer

Transfer cell-type labels between AnnData objects using weighted KNN mapping.

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omicverseomicverse
13

omicverse-single-cell-cytotrace2

Predict single-cell developmental potency from AnnData with OmicVerse CytoTRACE2.

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omicverseomicverse
13

omicverse-bulk-metabol-untargeted-lipidomics

Analyze untargeted LC-MS metabolomics and lipidomics data in AnnData.

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omicverseomicverse
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omicverse-single-cell-preprocessing

Convert OmicVerse single-cell AnnData objects into cluster-ready preprocessing and marker-discovery workflows.

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omicverseomicverse
13

omicverse-microbiome-16s-amplicon-dada2

Builds 16S amplicon analysis from FASTQs to AnnData with taxonomy and diversity.

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omicverseomicverse
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omicverse-microbiome-phylogeny

Build phylogenetic trees and compute tree-aware diversity metrics from 16S amplicon data.

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omicverseomicverse
13

omicverse-micro-metabol-paired

Detect microbe-metabolite associations across matched samples using Spearman correlation, CCA, and MMvec workflows.

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omicverseomicverse
13

omicverse-single-cell-annotation

Annotate clustered AnnData objects with OmicVerse cell-type labels.

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omicverseomicverse
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omicverse-single-cell-batch-integration

Run OmicVerse single-cell batch integration on preprocessed AnnData objects.

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omicverseomicverse
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omicverse-single-cell-metatime-annotation

Annotate tumor single-cell AnnData objects with MetaTiME cell-state labels.

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omicverseomicverse
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omicverse-bulk-metabol-preprocessing

Preprocess metabolomics peak tables into analysis-ready AnnData objects.

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omicverseomicverse
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omicverse-bulk-metabol-multivariate

Discriminate two metabolomics groups and select biomarkers from preprocessed AnnData.

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omicverseomicverse
13

omicverse-single-cell-differential-expression

Run single-cell differential expression analysis on AnnData datasets with Wilcoxon, t-test, or memento-de workflows.

Official
Advanced

Frequently Asked Questions About omicverse

FAQPage Schema
What specific biological data analysis tasks does Omicverse support?

Omicverse enables end-to-end processing of single-cell RNA-seq, spatial transcriptomics, bulk RNA-seq, and microbiome data. It supports tasks including cell-type annotation, trajectory inference, ligand-receptor communication mapping, differential expression analysis, and multi-omics data integration using standardized AnnData objects.

Who is the target user for these computational analysis methods?

The target users are bioinformaticians, computational biologists, and genomics researchers who require standardized, interoperable methods for processing high-dimensional biological datasets. It is designed for researchers performing secondary and tertiary analysis on sequencing data generated from platforms like 10x Genomics or LC-MS.

What are the primary dependencies for running these analysis methods?

Omicverse relies on the AnnData ecosystem and integrates with standard libraries such as Scanpy, SciPy, and StatsModels. Users must have a local environment capable of handling large-scale matrix operations and should be familiar with standard bioinformatics file formats like h5ad, gmt, and fastq.