alterlab-glycoengineering
CommunityAnalyze glycosylation and engineer glycoproteins
Education & Research#bioinformatics#protein-sequences#antibodies#glycosylation#glycoengineering#N-glycosylation#O-glycosylation
AuthorAlterLab-IEU
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Analyze and engineer protein glycosylation by scanning sequences for N-glycosylation sequons and predicting O-glycosylation hotspots, providing access to curated glycoengineering tools for glycoprotein design and optimization.
Core Features & Use Cases
- N-glycosylation sequon scanning: Identify canonical motifs N-X-[S/T] with X ≠ P.
- O-glycosylation hotspot prediction: Flag Ser/Thr-rich regions likely to bear O-glycans.
- Tool integration: Access NetOGlyc, GlycoShield, and GlycoWorkbench for predictions and exploratory analysis.
- Use Case: Guide therapeutic antibody engineering or vaccine antigen design by modulating glycosylation patterns to improve stability, PK, or immunogenicity.
Quick Start
Provide a protein sequence to analyze N- and O-glycosylation sites and receive site-level results plus suggested resources.
Dependency Matrix
Required Modules
None requiredComponents
references
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: alterlab-glycoengineering Download link: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/archive/main.zip#alterlab-glycoengineering Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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