alterlab-jaspar
CommunityQuery TF binding motifs with JASPAR.
AuthorAlterLab-IEU
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill enables researchers to retrieve and interpret transcription factor binding profiles from JASPAR, enabling rapid identification of potential TF binding sites in DNA sequences and facilitating motif-based analyses.
Core Features & Use Cases
- Search & retrieve JASPAR TF binding profiles and matrices via REST API to support motif discovery.
- PWM/PFM conversion & analysis: convert PFMs to PWMs and interpret binding affinities for target sequences.
- Sequence scanning: detect potential transcription factor binding sites on forward and reverse strands across user-provided sequences.
- Use Case: interpret regulatory variants by assessing motif disruption or creation in GWAS or fine-mapping contexts.
Quick Start
Scan a DNA sequence with a JASPAR matrix to identify potential transcription factor binding sites.
Dependency Matrix
Required Modules
None requiredComponents
references
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: alterlab-jaspar Download link: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/archive/main.zip#alterlab-jaspar Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
Agent Skills Search Helper
Install a tiny helper to your Agent, search and equip skill from 471,000+ vetted skills library on demand.