alterlab-medchem

Community

Filter drug-like compounds with medchem rules.

AuthorAlterLab-IEU
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Medicinal chemistry teams need scalable, rule-based filtering to triage large compound libraries for drug-likeness and safety.

Core Features & Use Cases

  • Applies Lipinski and Veber rules, PAINS filters, and structural alerts to molecules.
  • Computes complexity metrics and supports constraint-based filtering for library curation.
  • Use Case: triage a 100k-molecule library to identify drug-like leads for hit-to-lead optimization.

Quick Start

Run the medchem workflow on a molecule list to filter by rules, alerts, and complexity.

Dependency Matrix

Required Modules

pandasdatamolmedchemrdkittqdm

Components

scriptsreferences

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: alterlab-medchem
Download link: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/archive/main.zip#alterlab-medchem

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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