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AlterLab-IEU
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alterlab-open-notebook

Manage and analyze research materials with a self-hosted AI notebook.

58|9|Updated Mar 16, 2026
Search Tags:#research#api#privacy#self-hosted#open-notebook#ai-notebook
One-click install
npx skills add https://github.com/AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-open-notebook
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: alterlab-open-notebook
Source: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/tree/main/skills/document-tools/alterlab-open-notebook
Command: npx skills add https://github.com/AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-open-notebook

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

Open Notebook provides researchers with a self-hosted, privacy-preserving platform to organize materials, run AI-powered analyses, and collaborate with documents without relying on external services.

Core Features & Use Cases

  • Notebooks, Sources, Notes: organize research artifacts and capture context-aware conversations.
  • Context-aware Chat & Search: discuss with your materials and retrieve citations across sources.
  • Podcast generation and content transformations: create narrated summaries and extract insights from notebooks.
  • REST API with multi-provider support: integrate programmatically and swap AI providers (OpenAI, Anthropic, Google GenAI, Ollama, Groq, Mistral, etc.) without code changes.
  • Self-hosted data sovereignty: keep data on your infrastructure with encrypted credential storage. Use cases: research brainstorming, literature reviews, project documentation, and AI-assisted note-taking.

Quick Start

Install Docker, set OPEN_NOTEBOOK_ENCRYPTION_KEY, run docker-compose up -d, and open http://localhost:8502 for the UI and http://localhost:5055 for the API.

Frequently Asked Questions about alterlab-open-notebook

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I set up a self-hosted AI notebook for private research?▼

You can deploy this self-hosted AI notebook using Docker by setting an encryption key and running docker-compose. This keeps your research materials and AI analyses private on your own infrastructure, accessible via local web ports.

Can I use multiple AI providers like OpenAI and Ollama for document chat?▼

Yes, the system supports multi-provider AI integration including OpenAI, Anthropic, Google GenAI, Ollama, Groq, and Mistral. You can swap AI providers programmatically via REST API without code changes for context-aware document chat.

What is context-aware search for literature reviews and how does it work?▼

Context-aware search allows you to discuss your uploaded sources and retrieve citations directly across your research materials. It works by organizing notebooks, sources, and notes to capture conversations and extract insights for literature reviews.

How do I generate podcasts or narrated summaries from research documents?▼

You can generate podcasts and narrated summaries using the content transformation features of your self-hosted notebook. It extracts insights from your organized research artifacts to create audio outputs from text documents.

Does Open Notebook support REST API access for programmatic research workflows?▼

Yes, Open Notebook exposes a REST API for programmatic integration into research workflows. It allows you to manage notebooks, sources, and notes while maintaining data sovereignty with encrypted credential storage.

What are the limitations of self-hosting an AI notebook for research?▼

Self-hosting requires managing your own Docker infrastructure and encryption keys. You need sufficient local compute resources depending on the AI providers used, though data sovereignty and privacy are fully maintained.

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