alterlab-rdkit

Community

RDKit-powered cheminformatics toolkit

AuthorAlterLab-IEU
Version1.0.0
Installs0

System Documentation

What problem does it solve?

RDKit-enabled workflows for researchers seeking to perform end-to-end cheminformatics tasks, including molecular I/O, descriptor calculations, fingerprinting, substructure search, coordinate generation, similarity, and reaction analysis, in a single, structured guide.

Core Features & Use Cases

  • RDKit-based molecular I/O: read/write SMILES, MOL, SDF, PDB, InChI, and more.
  • Descriptor calculation: compute MW, LogP, TPSA, HBD/HBA, rotatable bonds, and advanced metrics.
  • Fingerprints & similarity: Morgan/ECFP-like fingerprints, MACCS keys, and pairwise similarity scoring.
  • Substructure searching: SMARTS patterns and substructure matches for rapid screening.
  • 2D/3D generation and visualization: coordinate generation, conformer generation, and alignment.
  • Reactions: basic reaction definitions and product generation via SMARTS-based transforms.

Quick Start

Process a SMILES string to compute descriptors, fingerprints, and substructure matches using RDKit.

Dependency Matrix

Required Modules

rdkit

Components

scriptsreferences

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: alterlab-rdkit
Download link: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/archive/main.zip#alterlab-rdkit

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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