apsiii-score

Compute APS III scores from first-day ICU data to predict hospital mortality.

40|17|Updated Oct 27, 2025
One-click install
npx skills add https://github.com/hannesill/m4 --skill apsiii-score
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: apsiii-score
Source: https://github.com/hannesill/m4/tree/main/src/m4/skills/clinical/apsiii-score
Command: npx skills add https://github.com/hannesill/m4 --skill apsiii-score

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) components.

What problem does it solve?

The APS III scoring algorithm provides a standardized, reproducible severity measure for ICU patients on the first day of admission, enabling reliable mortality risk stratification and cohort benchmarking.

Core Features & Use Cases

  • Calculates the Acute Physiology Score III (APS III) using vital signs, laboratory values, pH/pCO2 interaction, urine output, and ventilation status.
  • Outputs the overall APS III score, ARF status modifier, acid-base interaction score, and predicted mortality probability suitable for risk-adjusted analyses.
  • Use Case: compare severity across ICU stays, adjust for case-mix in research studies, and track severity trends over time.

Quick Start

Run the APS III scoring on the first ICU day to compute the apsiii score and its mortality probability.

Frequently Asked Questions about apsiii-score

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I calculate the APS III severity score for ICU patients using first-day data?

To calculate the APS III severity score, you process first-day ICU vital signs, labs, GCS, urine output, and ventilation data. The computation outputs the overall score, ARF modifier, acid-base interaction score, and predicted mortality probability for adult ICU stays.

What is the APS III score and how does it predict ICU mortality?

The APS III score is a standardized severity measure quantifying illness severity for ICU patients on the first day of admission. It predicts hospital mortality probability using physiological variables, urine output, and ventilation status for risk stratification.

Can I use APS III scoring for cohort benchmarking and case-mix adjustment in clinical research?

Yes, APS III scoring supports ICU mortality risk stratification, benchmarking, and cohort analysis across admissions. It provides a reproducible severity measure to compare severity across ICU stays and adjust for case-mix in clinical research studies.

Does the APS III calculation handle acid-base interactions and ARF modifiers?

Yes, the APS III calculation encapsulates scoring logic for acid-base interactions using pH and pCO2 values, and applies ARF status modifiers. These components adjust the final severity score and predicted mortality probability based on acute renal failure status.

How do I compute APS III scores for adult ICU stays using MIMIC-IV derived tables?

You compute APS III scores for adult ICU stays by integrating first-day physiological data from derived tables. The scoring algorithm processes vital signs, laboratory values, and ventilation data to output severity scores and mortality probabilities for MIMIC-IV cohorts.