atacseq

Execute the nf-core/atacseq workflow for ATAC-seq alignment, peak calling, QC, and differential analysis.

1|Updated Jun 19, 2026
One-click install
npx skills add https://github.com/danilomonge/nf-claw --skill atacseq
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: atacseq
Source: https://github.com/danilomonge/nf-claw/tree/main/pipelines/atacseq
Command: npx skills add https://github.com/danilomonge/nf-claw --skill atacseq

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

This Skill removes the manual guesswork from running the nf-core/atacseq workflow by turning a validated samplesheet and parameter set into a reproducible ATAC-seq analysis run with the correct pinned release, outputs, and provenance.

Core Features & Use Cases

  • Release-pinned execution: Runs the exact tracked atacseq release so results stay consistent with the repository state.
  • End-to-end ATAC-seq analysis: Supports sample input validation, alignment, peak calling, QC, and differential analysis in one workflow.
  • Research-ready output: Produces organized results, pipeline metadata, and MultiQC reporting for downstream interpretation and sharing.
  • Use case: A bioinformatics researcher can submit a CSV samplesheet and get a complete, reproducible ATAC-seq results directory without hunting through upstream documentation.

Quick Start

Ask the Skill to run the atacseq pipeline on your samplesheet, confirm the required parameters, and generate a reproducible results directory.

Frequently Asked Questions about atacseq

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I run a reproducible ATAC-seq pipeline from a samplesheet?

To run a reproducible ATAC-seq pipeline, provide a validated CSV samplesheet and configurable parameters to execute the nf-core/atacseq workflow with release-pinned consistency and provenance capture.

What does end-to-end ATAC-seq data analysis include?

End-to-end ATAC-seq data analysis includes sample input validation, alignment, peak calling, quality control, and differential analysis, generating organized results with MultiQC reporting for downstream interpretation.

Do I need a schema-checked samplesheet for ATAC-seq peak calling?

Yes, a schema-checked samplesheet is required for ATAC-seq peak calling to ensure validated sample inputs and strict parameter compliance before Nextflow execution begins.

Can I use custom reference genomes with the nf-core atacseq workflow?

Yes, the nf-core atacseq workflow accepts optional reference genomes alongside configurable analysis profiles, allowing customized ATAC-seq alignment and peak calling across supported Nextflow engine versions.

Why are my ATAC-seq pipeline results inconsistent across different runs?

ATAC-seq pipeline results become inconsistent without release-pinned execution, but this workflow tracks the exact atacseq repository release to maintain reproducible outputs and provenance across runs.