bio-clinical-databases-tumor-mutational-burden

Name: bio-clinical-databases-tumor-mutational-burden
Availability: InStock
Author: stellaromics

Official

Compute TMB with panel-aware normalization.

Data & Analytics #genomics #vcf #panel #tmb #tumor-mutational-burden #cyvcf2 #immunotherapy

Authorstellaromics

Version1.0.0

Installs0

System Documentation

What problem does it solve?

Calculate tumor mutational burden from panel or WES data with proper normalization and clinical thresholds to support immunotherapy decision-making.

Core Features & Use Cases

Compute TMB from somatic VCFs with panel-aware normalization and panel-size references.
Support FDA-like thresholds for classification and optional MSI comparison.
Enable batch processing across cohorts and export summary tables.

Quick Start

Provide a somatic VCF path and a panel name to compute TMB with panel normalization and output the results.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: bio-clinical-databases-tumor-mutational-burden
Download link: https://github.com/stellaromics/fast-bioinfo/archive/main.zip#bio-clinical-databases-tumor-mutational-burden

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.

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