bio-crispr-screens-batch-correction
OfficialBatch-effect correction for CRISPR screens.
Authorstellaromics
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Batch effect correction for CRISPR screens. It covers normalization across batches, handling technical replicates, and enabling batch-aware analysis.
Core Features & Use Cases
- Median normalization, size-factor normalization, quantile normalization, and ComBat-style batch adjustment.
- Batch-aware analysis workflows including replicate QC and batch QC metrics.
- Use cases include combining data from multiple CRISPR screens or sites while preserving biological signal.
Quick Start
Provide a batch-corrected count matrix by applying median normalization or ComBat to your CRISPR screen dataset.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
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Please help me install this Skill: Name: bio-crispr-screens-batch-correction Download link: https://github.com/stellaromics/fast-bioinfo/archive/main.zip#bio-crispr-screens-batch-correction Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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