bio-tcr-bcr-analysis-immcantation-analysis
CommunityAnalyze BCR repertoires with Immcantation.
Data & Analytics#clonality#bcr#immcantation#somatic-hypermutation#lineage-trees#airr#germline-inference
Authorya-way
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Analyze BCR repertoires for somatic hypermutation, clonal evolution, and lineage reconstruction using the Immcantation framework to study affinity maturation and antibody dynamics.
Core Features & Use Cases
- Load AIRR-formatted BCR data and annotate V(D)J genes
- Cluster sequences into clonal lineages, quantify SHM, and infer ancestral relationships
- Build and visualize clonal lineage trees, test for selection, and infer germline alleles
- Integrate Immcantation tools (alakazam, shazam, tigger, dowser) for end-to-end analyses
Quick Start
Load your BCR AIRR data into the Immcantation workflow, perform clonality analysis, and generate lineage trees in a single run.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: bio-tcr-bcr-analysis-immcantation-analysis Download link: https://github.com/ya-way/cytoclaw-skills/archive/main.zip#bio-tcr-bcr-analysis-immcantation-analysis Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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