bio-tcr-bcr-analysis-scirpy-analysis
CommunityAnalyze single-cell TCR/BCR data with scirpy.
Authorya-way
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Analyze single-cell TCR and BCR data integrated with gene expression using scirpy. Use when working with 10x Genomics VDJ data alongside scRNA-seq or when integrating immune receptor information with cell state analysis.
Core Features & Use Cases
- Load VDJ data and attach receptor metadata to AnnData
- Define clonotypes from CDR3 sequences
- Assess clonal expansion and repertoire diversity
- Visualize V gene usage, spectratype, and integrated plots with gene expression
- Export clonotype summaries for downstream tools
Quick Start
Load your 10x VDJ data into an AnnData object and run clonotype analysis to identify expanded clones.
Dependency Matrix
Required Modules
None requiredComponents
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Please help me install this Skill: Name: bio-tcr-bcr-analysis-scirpy-analysis Download link: https://github.com/ya-way/cytoclaw-skills/archive/main.zip#bio-tcr-bcr-analysis-scirpy-analysis Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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