bio-viromics

Detect viral contigs, classify taxonomy, and assess genome quality with geNomad, vConTACT3, and CheckV.

7|1|Updated Feb 2, 2026
One-click install
npx skills add https://github.com/fmschulz/omics-skills --skill bio-viromics
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: bio-viromics
Source: https://github.com/fmschulz/omics-skills/tree/main/skills/bio-viromics
Command: npx skills add https://github.com/fmschulz/omics-skills --skill bio-viromics

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Viromics workflows require detection, classification, and QC of viral contigs from metagenomic assemblies. This skill provides an integrated approach to identify viral sequences, assign taxonomy, and assess genome quality to streamline downstream analyses.

Core Features & Use Cases

  • Detect viral contigs using geNomad
  • Classify and cluster viral genomes with vConTACT3
  • Assess genome completeness and contamination with CheckV
  • Optional giant-virus taxonomy analysis with GVClass
  • Use cases: end-to-end viromics analysis from assembly to taxonomy and QC, ecological studies, and publication-ready datasets.

Quick Start

Provide contigs.fasta and reference databases, then run the bio-viromics workflow to generate viral contig detections, taxonomy outputs, and QC reports.

Frequently Asked Questions about bio-viromics

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I detect and classify viral contigs from metagenomic assemblies?

You can detect and classify viral contigs by running an integrated viromics workflow that uses geNomad for viral sequence detection and vConTACT3 for taxonomic clustering. This approach processes raw assemblies to identify and group viral genomes.

What is the best way to assess viral genome completeness and contamination?

The best way to assess viral genome completeness and contamination is to use CheckV within a viromics workflow. It evaluates assembled viral contigs to measure genome quality, ensuring your dataset meets publication-ready standards.

How do I run an end-to-end viromics analysis from raw assemblies to taxonomy?

To run an end-to-end viromics analysis, provide a contigs.fasta file and reference databases to a workflow integrating geNomad, vConTACT3, and CheckV. This generates viral contig detections, taxonomy outputs, and QC reports.

Can I classify giant viruses using metagenomic assemblies?

Yes, you can classify giant viruses from metagenomic assemblies by enabling the optional GVClass module. It provides specialized giant-virus taxonomy analysis alongside standard viral contig detection and classification.

Does this viral contig identification approach work for large-scale ecological studies?

Yes, this viral contig identification approach works for large-scale ecological studies. It is designed to detect viral sequences, cluster related genomes, and assess completeness at scale, directly supporting publication-ready datasets.