What problem does it solve? Bioinformatics spans hundreds of specialized domains, and bundling every pipeline locally is impractical. This Skill acts as a gateway that indexes over 400 bioinformatics skills from two open-source libraries and fetches the exact reference material or runnable pipeline needed for a given computational biology task. ## Core Features & Use Cases - Domain Index: Covers genomics, transcriptomics, single-cell analysis, variant calling, pharmacogenomics, metagenomics, structural biology, proteomics, CRISPR screens, and more, organized by domain. - Two Source Libraries: bioSkills provides 385 reference guides with code patterns and parameter best practices; ClawBio provides 33 executable pipelines with demo flags and reproducibility bundles. - On-Demand Fetching: Shallow-clones the relevant GitHub repository and reads the specific skill file rather than loading everything into context. - Use Case: When asked to annotate a VCF file, the Skill directs you to clone ClawBio and follow the vcf-annotator pipeline, which applies VEP, ClinVar, and gnomAD annotations with ancestry-aware context. ## Quick Start Ask the agent to run a differential expression analysis on your RNA-seq count matrix and it will fetch the appropriate DESeq2 or ClawBio rnaseq-de pipeline guidance.
