What problem does it solve?
Biomedical research requires pulling evidence from many disconnected sources (PubMed, ClinVar, registries, guidelines), and gaps in research tooling are discovered during sessions but rarely recorded. This Skill runs a disciplined research loop with the BioMCP CLI while capturing bugs and feature gaps as structured issues in the biomcp repository.
Core Features & Use Cases
- Guided research loop: Start with broad web search, confirm records with
biomcp get article and citation walking, then verify against primary sources like ClinGen and Europe PMC.
- Context discipline: Teaches bounded reading of cached full texts and filtered
--json output so large papers do not flood the session context.
- Evidence verification: Cross-checks joined cross-entity data against upstream sources (MyVariant, Europe PMC, NCBI) before trusting it, and reports negative results honestly.
- Structured feedback filing: Writes bugs and feature requests as kebab-case issue files with severity levels, reproduction evidence, and root-cause analysis for later triage.
- Use Case: While investigating a PTEN variant classification, use the Skill to pull the paper record via BioMCP, verify assertions in the ClinGen Evidence Repository, and file a feature issue documenting that filtering allele frequency is not reported by any existing command.
Quick Start
Ask the assistant to research a gene, variant, or paper using BioMCP and to file any tool limitations it encounters as issues in the biomcp repo.
