Predict protein complex structures with Boltz-1/Boltz-2 and output CIF models.
npx skills add https://github.com/adaptyvbio/protein-design-skills --skill boltz
Please help me install this Agent Skill. Skill: boltz Source: https://github.com/adaptyvbio/protein-design-skills/tree/main/skills/boltz Command: npx skills add https://github.com/adaptyvbio/protein-design-skills --skill boltz
Boltz provides an open-source, GPU-friendly pathway for predicting protein complex structures using Boltz-1 and Boltz-2, filling gaps left by closed tools and enabling local experimentation.
Run Boltz to predict a complex: modal run modal_boltz.py --input-faa complex.fasta --out-dir predictions/
High-intent search queries and answers about installing and using this skill.
You can predict protein complex structures by running Boltz-1 or Boltz-2 via a Python workflow. It processes an input FASTA file and outputs CIF models along with confidence metrics and PAE matrices.
Running Boltz locally requires Python 3.10 or higher and CUDA-enabled GPUs. The workflow supports local installations to predict complexes and output CIF models without relying on cloud resources.
Yes, Boltz supports Modal-based deployment to run structure prediction on remote GPUs. You execute a Python script with your input FASTA file and output directory to generate predicted complexes.
Validating designed binders with Boltz outputs CIF structural models, confidence metrics including ptm, iptm, and pLDDT scores, and PAE matrices to help assess prediction quality.
Yes, Boltz supports predicting protein-ligand complexes using its open-source models. It generates CIF models and confidence metrics for the predicted interactions.
Boltz provides an open-source alternative for protein complex prediction when local GPU resources are preferred or closed tools are unavailable. It runs via Modal or local Python environments to generate comparable structural outputs.
junior1pPredict biomolecular structures with Boltz-1 and Boltz-2 on local GPUs.
adaptyvbioPredict protein structures from FASTA sequences using Chai-1.
PKU-YuanGroupPredict protein, nucleic-acid, and small-molecule complex structures with Chai-1.
zongtingweiPredict protein and complex structures with Boltz-1 / Boltz-2 and output CIF files.
