by-causal-reasoning

Generate ranked, evidence-grounded hypotheses from diagnostic features.

104|10|Updated Mar 23, 2026
One-click install
npx skills add https://github.com/001TMF/blatant-why --skill by-causal-reasoning
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: by-causal-reasoning
Source: https://github.com/001TMF/blatant-why/tree/main/templates/.claude/skills/by-causal-reasoning
Command: npx skills add https://github.com/001TMF/blatant-why --skill by-causal-reasoning

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

Translates discriminating diagnostic features into canonical, evidence-grounded mechanistic hypotheses anchored in a knowledge graph, enabling auditable explanations for design failures.

Core Features & Use Cases

  • Maps discriminating features to canonical mechanisms using a knowledge graph, providing traceable rationale.
  • Generates up to five hypotheses, each with structured supporting and contradicting evidence, and a falsifiable prediction.
  • Provides downstream guidance for campaigns (e.g., optimization, hypothesis debate, or knowledge-store updates) based on confidence and evidence mix.

Quick Start

Run the generate_hypotheses.py workflow with a diagnosis.json and knowledge graph data to produce hypotheses.json for downstream analysis.

Frequently Asked Questions about by-causal-reasoning

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I generate evidence-grounded hypotheses for protein design failures?

To generate evidence-grounded hypotheses for protein design failures, map your discriminating diagnostic features to a knowledge graph. This translates structural context into ranked, canonical mechanisms with traceable rationale and falsifiable predictions.

What is causal reasoning for identifying failure mechanisms from diagnostic features?

Causal reasoning for failure mechanisms maps diagnostic features to canonical mechanisms using a knowledge graph. It provides auditable explanations by enforcing evidence grounding, assigning confidence via a precedence table, and outputting up to five ranked hypotheses.

How do I use a knowledge graph to create falsifiable predictions for design campaigns?

You can use a knowledge graph to create falsifiable predictions by running a script with your diagnosis data and knowledge graph inputs. The workflow outputs structured hypotheses, each containing supporting evidence, contradicting evidence, and a specific prediction.

Do I need structured diagnostics to perform causal reasoning on design failures?

Yes, structured diagnostics are required to identify underlying failure mechanisms. Optional structural context can be added to the diagnostics to further anchor the generated mechanistic hypotheses and improve the traceable rationale.

What downstream guidance does causal reasoning provide after generating mechanistic hypotheses?

Downstream guidance depends on the assigned confidence and evidence mix of the generated hypotheses. It directs your campaigns toward specific next steps, including optimization, hypothesis debate, or knowledge-store updates.

Can I get auditable explanations for design failures without manually tracing evidence?

Yes, you can obtain auditable explanations for design failures by anchoring diagnostic features in a knowledge graph. The system automatically cites supporting and contradicting evidence per hypothesis, ensuring traceable rationale without manual tracing.