celltype-deconvolution

Community

Deconvolve spatial data to per-spot cell types.

Authorchenyhvvvv
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Spatial transcriptomics analysis often lacks per-spot cell-type resolutions; this skill provides reference-based deconvolution using RCTD to infer cell-type proportions for each spatial feature.

Core Features & Use Cases

  • RCTD-based deconvolution: estimates cell-type proportions per spatial spot using a single-cell reference.
  • Dominant cell type assignment: derives a per-spot main cell type for visualization.
  • Use Case: annotate tumor microenvironments on Visium slides by mapping spots to immune and tumor cell types.

Quick Start

Provide a spatial dataset and a linked annotated single-cell reference to run the deconvolution.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

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Please help me install this Skill:
Name: celltype-deconvolution
Download link: https://github.com/chenyhvvvv/STAT-agent/archive/main.zip#celltype-deconvolution

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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