circdna

What problem does it solve?

This Skill removes the guesswork from running the nf-core/circdna workflow so you can identify circular DNA in sequencing datasets with the right inputs, options, and release-specific behavior from the start.

Core Features & Use Cases

• Circular DNA detection: Supports analysis paths for extrachromosomal circular DNA discovery across WGS, ATAC-seq, and Circle-Seq style data.
• Reproducible pipeline execution: Works with pinned Nextflow releases, validated parameters, and documented outputs so runs are easy to repeat and audit.
• Practical research workflows: Helps bioinformatics users choose the correct input format, circular DNA identifier, and optional preprocessing or reference settings for their dataset.
• Example use case: A researcher can submit a samplesheet for paired-end sequencing reads, select the appropriate detection branch, and produce standardized result folders plus provenance records for downstream interpretation.

Quick Start

Use the circdna skill to run nf-core/circdna on your samplesheet with the required input format, outdir, and circle identifier for your dataset.