clinpgx

Query ClinPGx for gene and drug annotations and export markdown, CSV, and JSON reports.

1.1k|238|Updated Feb 25, 2026
One-click install
npx skills add https://github.com/ClawBio/ClawBio --skill clinpgx
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: clinpgx
Source: https://github.com/ClawBio/ClawBio/tree/main/skills/clinpgx
Command: npx skills add https://github.com/ClawBio/ClawBio --skill clinpgx

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

ClinPGx simplifies retrieving authoritative pharmacogenomic gene-drug information by querying the ClinPGx REST API and aggregating clinical annotations, guideline recommendations, and regulatory drug label statements so researchers and clinicians can quickly find evidence for gene-drug interactions.

Core Features & Use Cases

  • Gene lookup: Retrieve gene metadata, allele types, and CPIC gene flags for pharmacogenes such as CYP2D6 or CYP2C19.
  • Drug lookup: Search drugs by name and collect linked clinical annotations and FDA/EMA label statements.
  • Gene-drug pair analysis: Aggregate clinical annotations, CPIC/DPWG guidelines, and drug labels for specific gene-drug pairs and produce reproducible reports and CSV tables.
  • Operational features: Built-in rate limiting (2 req/sec), local 24-hour caching, CLI and programmatic API integration, and standardized JSON result export for reproducibility.
  • Use case: Query a list of pharmacogenes to generate a markdown report and CSV tables summarizing clinical evidence and dosing guidance for flagged gene-drug pairs.

Quick Start

Look up CYP2D6 and warfarin on ClinPGx and generate a markdown report with CSV tables of clinical annotations, guidelines, and drug labels.

Frequently Asked Questions about clinpgx

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve CPIC and DPWG pharmacogenomic guidelines for specific gene-drug pairs?

To retrieve CPIC and DPWG pharmacogenomic guidelines for specific gene-drug pairs, query the ClinPGx API to aggregate clinical annotations, guideline recommendations, and regulatory drug label statements into structured evidence.

Can I batch lookup pharmacogenes like CYP2D6 and export the clinical annotations to CSV?

Yes, you can perform batch lookups for pharmacogenes like CYP2D6 and export the retrieved clinical annotations, allele definitions, and dosing guidance to CSV tables and markdown reports.

What pharmacogenomic data sources are available for gene-drug interaction analysis?

Available pharmacogenomic data sources for gene-drug interaction analysis include ClinPGx clinical annotations, CPIC and DPWG guideline recommendations, and FDA and EMA regulatory drug label statements.

Does ClinPGx API rate limiting affect pharmacogenomic lookup workflows?

ClinPGx enforces a built-in rate limit of two REST API requests per second with local 24-hour caching to manage pharmacogenomic lookup workflows efficiently without exceeding API constraints.

How do I generate reproducible markdown reports for pharmacogenomic gene-drug evidence?

Generate reproducible markdown reports for pharmacogenomic gene-drug evidence by querying ClinPGx for clinical annotations and guidelines, then exporting the aggregated results as standardized JSON summaries and markdown files.