coexpression-for-gene

Community

Discover genes co-expressed with a query gene.

AuthorMDhewei
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Co-expression for Gene identifies genes whose expression patterns correlate with a query gene across TCGA PanCancer Atlas patient samples and GTEx normal tissues, enabling discovery of functionally related genes and co-expression networks.

Core Features & Use Cases

  • Data-driven discovery of gene modules by correlating a query gene with all other genes across selected datasets.
  • Supports TCGA pan-cancer analysis via cBioPortal REST API and GTEx with a user-provided expression matrix.
  • Outputs include coexpression_results.tsv, top_coexpressed.png, coexpression_network.png, and an optional GO enrichment/summary report.

Quick Start

Provide a gene symbol and dataset options to compute its co-expression across TCGA and GTEx data.

Dependency Matrix

Required Modules

pandasnumpymatplotlibscipyrequests

Components

scripts

💻 Claude Code Installation

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Please help me install this Skill:
Name: coexpression-for-gene
Download link: https://github.com/MDhewei/bioinfor-claw/archive/main.zip#coexpression-for-gene

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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