compchem-chemprop-prediction

Community

Predict acute toxicity data with Chemprop MPNN.

Authorwuyoscar
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Automates the creation and validation of toxicity-focused ML datasets by aligning SMILES data, LD50 values, and mechanism descriptions, then training a Chemprop MPNN to predict acute toxicity endpoints.

Core Features & Use Cases

  • Data validation: checks SMILES parsing, LD50 thresholds (<50 mg/kg), and mechanism language guidelines.
  • Model-training workflow: prepares a regression dataset and runs cross-validated Chemprop training.
  • Use cases: toxicology data completion, rapid LD50 prediction for new compounds, and guideline-compliant dataset curation.

Quick Start

Run a dataset with the required columns through the workflow to train and validate a Chemprop model.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: compchem-chemprop-prediction
Download link: https://github.com/wuyoscar/ISC-Bench/archive/main.zip#compchem-chemprop-prediction

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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