complexa-setup

To set up the protein design environment, you can run an automated configuration process that creates the .env file, builds the Python virtual environment, and performs pre-flight hardware checks.

Biomolecular modeling with Proteina-Complexa requires specific GPU capabilities and over 100GB of available disk space to store model weights. The setup process validates hardware and disk availability before execution.

Downloading model checkpoints for binder generation and motif scaffolding is managed automatically during environment initialization, routing specific weights like Protein Binder, Ligand Binder, and AME to the correct local paths.

Yes, the environment configuration supports downloading and integrating community models like AF2 and RF3 alongside native checkpoints, ensuring all required tool dependencies are validated for reliable scientific pipeline execution.

Environment configuration can fail if system hardware requirements are not met, disk availability is insufficient for the 100GB+ model weights, or required tool dependencies are missing from your system.