coproid

Run the nf-core/coproid pipeline for host DNA identification in paleofaeces samples.

1|Updated Jun 19, 2026
One-click install
npx skills add https://github.com/danilomonge/nf-claw --skill coproid
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: coproid
Source: https://github.com/danilomonge/nf-claw/tree/main/pipelines/coproid
Command: npx skills add https://github.com/danilomonge/nf-claw --skill coproid

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Coproid automates the analysis of complex Illumina metagenomic samples to help identify the true host signal in paleofaeces and related microbiome-rich material, avoiding manual flag hunting and release-specific confusion.

Core Features & Use Cases

  • Pinned pipeline execution: Runs the exact nf-core/coproid release bundled with the skill so results stay reproducible.
  • Schema-validated inputs: Uses a samplesheet plus required genome, kraken2, and sourcepredict reference tables to enforce correct parameter usage.
  • Provenance-aware workflows: Produces standardized outputs, MultiQC summaries, and run metadata for traceable downstream reporting.
  • Use case: A researcher can provide sequencing reads and the required reference tables to process a faecal metagenomics study and obtain host-identification results without having to inspect upstream documentation.

Quick Start

Ask me to run the coproid pipeline on your samplesheet with the required genome, kraken2, and sourcepredict inputs, and I will launch the pinned release into your chosen output directory.

Frequently Asked Questions about coproid

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I identify host DNA from paleofaeces metagenomic samples?

Host DNA identification from paleofaeces metagenomic samples uses the nf-core/coproid pipeline to compare microbiome composition, endogenous host DNA, and source-prediction signals across Illumina reads. This automated approach applies source-prediction to pinpoint the true host without manual flag hunting.

What inputs do I need to run a coproid host-identification workflow?

Running a coproid host-identification workflow requires an Illumina samplesheet in CSV format, reference genome inputs, and kraken2 and sourcepredict reference tables. You must also specify an output directory and schema-validated parameters with an explicit Nextflow version control.

Does the nf-core coproid pipeline support reproducible metagenomics analysis?

The nf-core coproid pipeline supports reproducible metagenomics analysis by running a pinned pipeline release bundled with the skill. This ensures standardized outputs, MultiQC summaries, and run metadata remain consistent across different analyses for traceable downstream reporting.

How do I process a faecal metagenomics study to obtain host-identification results?

To process a faecal metagenomics study for host-identification results, provide sequencing reads and the required reference tables to the pipeline. The schema-validated inputs enforce correct parameter usage, allowing you to obtain results without inspecting upstream documentation.

When should I use coproid for metagenomic host identification?

You should use coproid for metagenomic host identification when working with complex Illumina faecal metagenomic samples, especially paleofaeces and microbiome-rich material. It is designed to resolve true host signals when manual flag hunting and release-specific confusion become problematic.