cosmic-database

Downloads COSMIC genomic datasets including mutations, gene census, signatures, and structural variants via Python scripts.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill cosmic-database-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: cosmic-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/cosmic-database
Command: npx skills add https://github.com/yf8578/clawomics --skill cosmic-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, pysam, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the Catalogue of Somatic Mutations in Cancer (COSMIC) database, enabling users to download and analyze comprehensive cancer genomics data.

Core Features & Use Cases

  • Data Download: Download various COSMIC datasets including mutations, gene census, signatures, and structural variants.
  • Data Integration: Facilitates the integration of COSMIC data into bioinformatics pipelines for cancer research and precision oncology.
  • Use Case: Download the Cancer Gene Census to identify known cancer-driving genes for targeted therapy selection.

Quick Start

Use the cosmic-database skill to download the Cancer Gene Census file.

Frequently Asked Questions about cosmic-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I download COSMIC cancer mutation data programmatically?

You can download COSMIC cancer mutation data programmatically using Python scripts that handle user authentication and data retrieval for diverse genomic datasets. This enables automated access to somatic mutations, cancer gene census, and structural variants.

What type of cancer genomics datasets can I query from the COSMIC database?

From the COSMIC database, you can query somatic mutations, the cancer gene census, mutational signatures, and structural variants. These datasets support comprehensive cancer research and precision oncology applications.

Do I need an account to access the COSMIC mutation database?

Yes, accessing the COSMIC mutation database requires user authentication. You must provide your credentials within the Python scripts to authorize and handle data retrieval from the COSMIC repository.

Can I use pandas and pysam to analyze COSMIC datasets?

Yes, you can use pandas and pysam to analyze COSMIC datasets. The Skill integrates these dependencies to facilitate downloading and processing genomic data within your existing bioinformatics pipelines.

How do I get the Cancer Gene Census file for targeted therapy selection?

To get the Cancer Gene Census file for targeted therapy selection, use the Skill to query and download the specific dataset. This identifies known cancer-driving genes for your precision oncology research.