covalent-probe-discovery
CommunityDiscover novel covalent reactive handles for biological side-chains.
Software Engineering#drug discovery#literature mining#chemical biology#covalent probe#reactive handle
Authormr-johnee
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill systematically mines chemistry literature to identify novel covalent reactive handles capable of forming stable bonds with specific biological side-chain functionalities.
Core Features & Use Cases
- Literature Mining: Surveys chemistry literature for covalent reactive handles.
- Novelty Identification: Focuses on structures not present in the known-warhead database.
- Use Case: When a user needs to survey chemistry literature for novel cysteine-reactive warheads published between 2015 and 2025.
Quick Start
Use the covalent-probe-discovery skill to identify novel cysteine-reactive warheads published between 2015 and 2025.
Dependency Matrix
Required Modules
pythonrdkithttpxjsonschema
Components
scriptsreferencesassets
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: covalent-probe-discovery Download link: https://github.com/mr-johnee/pClaw/archive/main.zip#covalent-probe-discovery Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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