Drug-Repurposing-Hub

Query the Broad Institute Drug Repurposing Hub for drug annotations by name, target, or ID.

130|4|Updated Mar 13, 2026
One-click install
npx skills add https://github.com/QSong-github/DrugClaw --skill drug-repurposing-hub
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: Drug-Repurposing-Hub
Source: https://github.com/QSong-github/DrugClaw/tree/main/skills/drug_repurposing/repurposing_hub
Command: npx skills add https://github.com/QSong-github/DrugClaw --skill drug-repurposing-hub

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Researchers require rapid access to a curated, annotated library of drugs to identify repurposing opportunities. The Drug Repurposing Hub aggregates MOA, targets, disease areas, indications, clinical phase, and chemical identifiers to accelerate evidence-based decision making.

Core Features & Use Cases

  • Local lookup and batch search by drug name, Broad ID, InChIKey, MOA, target, disease area, or indication to retrieve structured annotations including clinical phase, MOA, targets, disease area, and indications.
  • Flexible input and result handling that supports single or batch queries and outputs machine-readable metadata for downstream workflows.
  • Evidence-backed outputs that preserve source IDs and metadata for traceability and integration into research pipelines.

Quick Start

Run a search for a drug name or Broad ID to retrieve MOA, targets, disease area, and clinical phase.

Frequently Asked Questions about Drug-Repurposing-Hub

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I find drug repurposing candidates by target and clinical phase?

Batch search drug repurposing data using drug names, Broad IDs, or InChIKeys. The Skill accepts single or multiple queries and returns machine-readable metadata including pert_iname, moa, target, disease_area, and broad_id for downstream integration.

Can I retrieve mechanism of action and disease area annotations for a specific drug?

Query a specific drug name or Broad ID to retrieve its mechanism of action and disease area annotations. The Skill returns structured metadata fields including moa, target, disease_area, and indication directly from the Broad Institute Drug Repurposing Hub.

What structured data fields are available when querying Broad Hub drugs for repurposing insights?

Querying Broad Hub drugs returns structured fields including pert_iname, moa, target, disease_area, indication, and broad_id. These annotations preserve source IDs and metadata for traceability in evidence-based drug discovery research pipelines.

Does drug repurposing evidence synthesis work with InChIKey and Broad ID inputs?

Yes, drug repurposing queries support InChIKey and Broad ID inputs. The Skill identifies and returns matching repurposing data from the Broad Institute Hub, supporting chemical identifier lookups alongside drug name, target, and indication searches.

What is the best way to search a curated drug library for repurposing opportunities?

Query by MOA, targets, disease area, or indication to search a curated annotated drug library for repurposing opportunities. The Skill aggregates clinical phase and chemical identifiers from the Broad Hub to accelerate evidence-based decision making.

Are there limitations when mapping clinical phases to indication data in drug repurposing workflows?

Mapping clinical phases to indication data is limited by the Broad Institute Drug Repurposing Hub's curation scope. The Skill returns available annotations for candidate compounds but cannot infer missing clinical phase or disease area data absent from the source library.