end-to-end-protein-design-workflow

What problem does it solve?

End-to-end protein design campaigns require coordinating many tools and steps, from target preparation and hotspot selection through backbone generation, sequence design, validation, and QC, which can be error-prone without a structured workflow.

Core Features & Use Cases

• End-to-end orchestration: guides the full pipeline from target preparation through final QC, enabling reproducible campaigns.
• Tool integration planning: aligns RFdiffusion, ProteinMPNN, ColabFold, and AlphaFold-based validation in a single workflow.
• Use Case: design binders for a target protein by coordinating backbone generation, sequence design, and structural validation with defined checkpoints.

Quick Start

Initiate a new protein-design project and follow the Phase 1 target preparation steps to prepare the target, hotspots, and initial design plan.