Design or optimize protein sequences, structures, and functions using ESM3 and ESM C models.
npx skills add https://github.com/jackspace/ClaudeSkillz --skill esm
Please help me install this Agent Skill. Skill: esm Source: https://github.com/jackspace/ClaudeSkillz/tree/main/skills/scientific-pkg-esm Command: npx skills add https://github.com/jackspace/ClaudeSkillz --skill esm
This Skill provides practical guidance and examples for using ESM3 and ESM C protein models, including both local usage and Forge-based inference.
Install dependencies and run a basic ESM3/Forge example.
High-intent search queries and answers about installing and using this skill.
ESM3 generates novel protein sequences through multimodal design conditioned on structure, function, and sequence constraints. Use GenerationConfig to set parameters, then invoke the model locally or via Forge API to produce sequences optimized for your specifications.
Yes. ESM3 supports structure prediction and inverse folding workflows—recovering sequences from target structures. Both capabilities work in local inference mode or Forge-based batch processing for scaled prediction across multiple proteins.
ESM3 performs multimodal protein design and generation; ESM C specializes in embedding extraction for sequences and structures. Choose ESM3 for design tasks and ESM C when you need numerical representations for downstream analysis or function conditioning.
Use Forge API for batch processing of protein design jobs in cloud environments. Forge handles distributed inference of ESM3 and ESM C models, eliminating local compute constraints and enabling high-throughput generation and embedding extraction.
Local inference requires GPU access, but Forge API removes this requirement by running ESM3 and ESM C in the cloud. Choose local execution for development; switch to Forge for production-scale or resource-constrained environments.
Yes. ESM C models produce numerical embeddings from sequences and structures, capturing biochemical properties. Export embeddings for downstream ML tasks, functional annotation, or as input to other protein analysis tools.
Estrella-231Generate protein sequences, predict structures, and extract embeddings with ESM3 and ESM C.
Yezez9Generate protein sequences and embeddings using ESM3 and ESM C.
LogauaEngstromDesign, analyze, and derive protein embeddings using ESM3 and ESM C models.
yf8578Generate protein sequences, predict structures, and extract embeddings using ESM3 and ESM C.
