evo2

Community

Genomic sequence scoring and generation with Evo 2

Authorguanxiaol
Version1.0.0
Installs0

System Documentation

What problem does it solve?

The evo2 Skill addresses the challenge of genomic sequence analysis by providing tools for scoring, embedding, and generating DNA sequences, enabling users to work with long-context genomic foundation models efficiently.

Core Features & Use Cases

  • Sequence Scoring: Compute per-nucleotide or per-sequence likelihoods for variant effect scoring.
  • Sequence Embedding: Embed genomic windows for downstream classification tasks.
  • Sequence Generation: Generate DNA sequences conditioned on a prefix.
  • Regulatory and Coding Region Scoring: Score regulatory or coding regions across species.
  • Use Case: A researcher could use this Skill to generate DNA sequences based on a specific prefix, analyze the likelihood of variant effects, or embed genomic sequences for classification.

Quick Start

Run the evo2 skill to score a DNA sequence using the following command:

python3 score_evo2.py --sequences "ATCG" * 50

Dependency Matrix

Required Modules

evo2

Components

scripts

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: evo2
Download link: https://github.com/guanxiaol/open-science/archive/main.zip#evo2

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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