evolvable-graph-diffusion-ot

Align structural and functional brain connectomes with learnable optimal transport for disease classification.

2|Updated Feb 12, 2026
One-click install
npx skills add https://github.com/hiyenwong/ai_collection --skill evolvable-graph-diffusion-ot
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: evolvable-graph-diffusion-ot
Source: https://github.com/hiyenwong/ai_collection/tree/main/collection/skills/evolvable-graph-diffusion-ot
Command: npx skills add https://github.com/hiyenwong/ai_collection --skill evolvable-graph-diffusion-ot

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Align structural and functional brain connectomes using a learnable optimal transport mechanism to improve disease classification and brain-network analysis, addressing the limitations of fixed SC-FC alignments.

Core Features & Use Cases

  • OT-based alignment: learns a transport plan to align SC and FC networks for more accurate downstream analysis.
  • Evolvable graph diffusion: dynamically captures higher-order dependencies across brain regions.
  • KAN node aggregation: uses neural spline-based transformations for flexible, non-linear feature integration.
  • Applications: brain disease classification (e.g., MDD, AD) and structure–function relationship studies in neuroimaging.

Quick Start

Input the SC and FC brain connectome matrices into the EDT-PA model to obtain a disease classification prediction.

Frequently Asked Questions about evolvable-graph-diffusion-ot

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I align structural and functional brain connectomes for disease classification?

Align structural and functional brain connectomes by inputting SC and FC matrices into the model, which uses a learnable optimal transport mechanism to drive accurate disease classification predictions.

What is evolvable graph diffusion and how does it model high-order dependencies in brain networks?

Evolvable graph diffusion is a mechanism that dynamically captures higher-order dependencies across brain regions, moving beyond fixed structural-functional alignments to improve multi-modal brain network analysis.

Can I use this optimal transport model for brain disease classification in PyTorch?

Yes, you can use this PyTorch-based model for brain disease classification by inputting your structural and functional connectome matrices to obtain predictions for conditions like MDD or AD.

How does KAN node aggregation work for multi-modal brain network analysis?

KAN node aggregation uses neural spline-based transformations to provide flexible, non-linear feature integration, enabling more accurate structure-function relationship studies in neuroimaging workflows.

What are the limitations of fixed SC-FC alignments compared to learnable optimal transport?

Fixed SC-FC alignments lack adaptability, whereas learnable optimal transport dynamically learns a transport plan to align structural and functional networks, addressing limitations of static approaches.

Do I need pre-computed structural and functional connectome matrices to use this model?

Yes, you need pre-computed structural connectivity and functional connectivity brain connectome matrices to input into the model to perform end-to-end optimal transport alignment and classification.