fastqrepair

Repair corrupted FASTQ files and restore valid sequencing reads.

1|Updated Jun 19, 2026
One-click install
npx skills add https://github.com/danilomonge/nf-claw --skill fastqrepair
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: fastqrepair
Source: https://github.com/danilomonge/nf-claw/tree/main/pipelines/fastqrepair
Command: npx skills add https://github.com/danilomonge/nf-claw --skill fastqrepair

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

This Skill automates the recovery and cleanup of damaged or noncompliant FASTQ data so sequencing runs can continue with valid reads and reliable quality control.

Core Features & Use Cases

  • FASTQ Recovery and Repair: Fixes corrupted FASTQ.gz files, removes invalid reads, and restores read pairing when possible.
  • Sequencing Workflow Automation: Runs the nf-core/fastqrepair pipeline with a samplesheet, required inputs, and reproducible output organization.
  • Quality Reporting: Produces cleaned FASTQ outputs, pipeline metadata, and MultiQC reports for downstream analysis and review.
  • Use Case: A bioinformatics analyst can take a messy paired-end sequencing dataset, repair the reads, and deliver a validated result set for the next pipeline stage.

Quick Start

Ask the assistant to run the fastqrepair pipeline on your samplesheet and save the cleaned outputs to your chosen results directory.

Frequently Asked Questions about fastqrepair

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I repair corrupted FASTQ files and recover paired-end reads?

You can repair corrupted FASTQ files by running the nf-core fastqrepair pipeline with a validated samplesheet, which removes invalid reads, restores read pairing, and generates cleaned outputs with MultiQC quality reports.

What does FASTQ read pair recovery do when sequencing data is noncompliant?

FASTQ read pair recovery fixes corrupted FASTQ.gz files and removes invalid reads to restore valid sequencing data, ensuring noncompliant datasets can continue through downstream bioinformatics pipelines with reliable quality control.

Can I use nf-core fastqrepair with a samplesheet for single-end and paired-end sequencing?

Yes, the nf-core fastqrepair workflow supports both single-end and paired-end samples. It requires a validated samplesheet input and enforces required parameters to execute read cleanup, pair recovery, and QC reporting reproducibly.

Do I need a validated samplesheet to run FASTQ repair workflows in Nextflow?

Yes, a validated samplesheet is required to run FASTQ repair workflows in Nextflow. The Skill enforces required parameters and uses pinned pipeline metadata to ensure deterministic execution and a reproducible output structure.

What is the best way to clean up messy paired-end sequencing datasets for the next pipeline stage?

The best way to clean up messy paired-end datasets is running the nf-core fastqrepair pipeline to repair reads, enforce required parameters, and deliver a validated result set with MultiQC reports ready for the next pipeline stage.