funcscan

Screen assembled contigs for functional genes with nf-core/funcscan workflows.

1|Updated Jun 19, 2026
One-click install
npx skills add https://github.com/danilomonge/nf-claw --skill funcscan
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: funcscan
Source: https://github.com/danilomonge/nf-claw/tree/main/pipelines/funcscan
Command: npx skills add https://github.com/danilomonge/nf-claw --skill funcscan

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

This Skill helps you run the nf-core/funcscan pipeline correctly without guessing flags, so you can screen assembled contigs and related sequence inputs for functional genes with reproducible, validated parameters.

Core Features & Use Cases

  • End-to-end functional screening: Coordinates antimicrobial peptide, antibiotic resistance, biosynthetic gene cluster, and CAZyme screening workflows from one command.
  • Release-pinned reproducibility: Uses the exact upstream pipeline release and documents the required inputs, outputs, and parameter constraints for dependable runs.
  • Practical bioinformatics use case: Use it when you have a samplesheet of contigs, proteins, GFFs, or GBKs and need a consistent analysis run that produces module outputs plus a MultiQC summary.

Quick Start

Ask the assistant to run the funcscan skill on your samplesheet, choose the output directory, and execute the pipeline with the appropriate profile for your environment.

Frequently Asked Questions about funcscan

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I screen assembled contigs for functional genes using Nextflow?

You can screen assembled contigs for functional genes by running the nf-core/funcscan pipeline with a validated samplesheet containing FASTA and annotation inputs. This coordinates antimicrobial peptide, antibiotic resistance, biosynthetic gene cluster, and CAZyme screening from one command.

What is the best way to run antimicrobial peptide and antibiotic resistance screening on contigs?

The best way to run antimicrobial peptide and antibiotic resistance screening is through the nf-core/funcscan workflow, which uses release-pinned Nextflow execution and strict parameter validation to ensure reproducible pipeline runs with documented input and output contracts.

Can I use a samplesheet with GFF and GBK files for biosynthetic gene cluster screening?

Yes, you can use a samplesheet with GFF and GBK files for biosynthetic gene cluster screening. The pipeline accepts samplesheets with contigs, proteins, GFFs, or GBKs to produce module outputs plus a MultiQC summary.

Do I need to pin a specific Nextflow release to reproduce functional gene screening results?

Yes, you need to pin a specific Nextflow release to reproduce functional gene screening results. The skill uses release-pinned Nextflow execution and documents required inputs, outputs, and parameter constraints for dependable, reproducible runs.

Why does my functional gene screening pipeline require strict parameter validation?

Functional gene screening requires strict parameter validation to ensure reproducible pipeline runs. Without validated parameters, the nf-core/funcscan workflow cannot guarantee consistent analysis outputs or dependable module results across different execution environments.

Are there limitations when screening contigs for CAZymes and biosynthetic gene clusters?

Screening contigs for CAZymes and biosynthetic gene clusters requires properly formatted samplesheets with FASTA and annotation inputs. Limitations arise if input contracts are not documented or if Nextflow execution is not release-pinned for reproducible runs.