gene-database

Query NCBI Gene database via E-utilities and Datasets API for gene metadata.

Updated Mar 15, 2026

Search Tags:#bioinformatics #genomics #ncbi #database query #annotation #gene

Ready to run

npx skills add https://github.com/sagunkayastha/claude_skills_collection --skill gene-database-sagunkayastha

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: gene-database
Source: https://github.com/sagunkayastha/claude_skills_collection/tree/main/scientific-databases/gene-database
Command: npx skills add https://github.com/sagunkayastha/claude_skills_collection --skill gene-database-sagunkayastha

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill streamlines the process of accessing and analyzing gene information from the NCBI Gene database, eliminating the need for manual web searches or complex API integrations.

Core Features & Use Cases

Gene Information Retrieval: Fetch detailed data for specific genes using their symbols or IDs.
Batch Processing: Efficiently query multiple genes simultaneously for large-scale analysis.
Use Case: When performing a literature review on a specific gene, use this Skill to quickly retrieve its official symbol, description, chromosomal location, and associated pathways to enrich your understanding.

Quick Start

Use the gene-database skill to find detailed information for the human gene with the symbol BRCA1.

Frequently Asked Questions about gene-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I retrieve NCBI Gene data like RefSeqs and GO annotations for a specific gene symbol?▼

To retrieve NCBI Gene data for a specific symbol, you can query the database using E-utilities like ESearch and EFetch. This returns comprehensive metadata including RefSeqs, GO annotations, and chromosomal locations for your target gene.

Can I perform batch lookups for multiple genes using the NCBI Datasets API?▼

Yes, you can perform batch lookups for multiple genes using the NCBI Datasets API. This facilitates efficient simultaneous querying of gene IDs to retrieve annotations for large-scale functional analysis.

What is the best way to get comprehensive gene metadata without manual NCBI web searches?▼

The best way to get comprehensive gene metadata without manual NCBI web searches is programmatic querying via E-utilities. This approach instantly retrieves official symbols, descriptions, and associated pathways directly from the NCBI Gene database.

Does querying the NCBI Gene database support both ESummary and Datasets API endpoints?▼

Querying the NCBI Gene database supports both ESummary and Datasets API endpoints. This provides flexible data retrieval options by combining ESearch, ESummary, EFetch, and Datasets API endpoints for comprehensive gene annotation.

Are there limitations when using E-utilities for large-scale gene annotation and functional analysis?▼

When using E-utilities for large-scale gene annotation, limitations may arise from API rate limits or query complexity. Batch processing via the Datasets API helps mitigate these constraints for functional analysis workflows.