gene-list-overlap
CommunityCompare gene lists for overlaps and enrichment.
AuthorMDhewei
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Compare 2 to 6 gene lists to identify shared genes, quantify overlaps, and assess enrichment against a background. This enables validation across experiments and discovery of consensus hits.
Core Features & Use Cases
- Compare 2–6 gene lists to compute intersection sizes, Jaccard similarity, and Fisher's exact test for enrichment.
- Generate publication-quality visualizations: Venn diagrams (up to 4 lists), UpSet plots, and a Jaccard heatmap.
- Outputs: overlap_summary.tsv, jaccard_matrix.tsv, and optional outputs for unique genes per list and all intersections.
Quick Start
Provide 2–6 labeled gene lists and run the tool to compute overlaps, enrichment, and generate Venn/UpSet visuals.
Dependency Matrix
Required Modules
pandasnumpymatplotlibscipy
Components
scripts
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: gene-list-overlap Download link: https://github.com/MDhewei/bioinfor-claw/archive/main.zip#gene-list-overlap Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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