gget

Query and synthesize bioinformatics database results for genes, proteins, and sequences.

Updated Jul 1, 2026
One-click install
npx skills add https://github.com/jasrajtulsi/GRAD-SCOPE --skill gget-jasrajtulsi
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: gget
Source: https://github.com/jasrajtulsi/GRAD-SCOPE/tree/main/.claude/skills/gget
Command: npx skills add https://github.com/jasrajtulsi/GRAD-SCOPE --skill gget-jasrajtulsi

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires gget, pandas, and includes scripts (resource) and references (resource) components.

What problem does it solve?

gget removes the friction of hopping across many separate bioinformatics websites and APIs by giving you one consistent way to search genes, retrieve sequences, inspect protein structures, analyze expression, and explore disease or drug associations.

Core Features & Use Cases

  • Gene discovery and annotation: search gene names, fetch Ensembl, UniProt, and NCBI metadata, and retrieve nucleotide or protein sequences.
  • Sequence, structure, and motif analysis: run BLAST, BLAT, MUSCLE, DIAMOND, PDB lookups, AlphaFold predictions, and ELM motif scans.
  • Expression and disease workflows: query ARCHS4, CELLxGENE, Bgee, Enrichr, OpenTargets, cBioPortal, COSMIC, viral datasets, and mouse specificity data.
  • Use case: a researcher can start with a gene symbol, expand to orthologs and sequences, check tissue expression, test disease links, and compile results into CSV or FASTA outputs for downstream analysis.

Quick Start

Use the gget skill to analyze the gene or sequence you provide, then return the most relevant database results, sequences, expression signals, and disease associations for your target organism.

Frequently Asked Questions about gget

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query multiple bioinformatics databases for gene sequences and protein structures in one workflow?

To query multiple bioinformatics databases for gene sequences and protein structures, this skill searches Ensembl, UniProt, and NCBI using a single gene symbol, retrieving nucleotide sequences, metadata, and AlphaFold predictions in one consistent pass.

What's the best way to fetch gene expression data and test disease associations from a gene list?

Fetching gene expression data and testing disease associations is handled by querying ARCHS4, CELLxGENE, and OpenTargets, returning tissue specificity signals and disease links compiled into tabular CSV output for downstream analysis.

Can I run BLAST sequence alignment and enrichment analysis directly against Ensembl and UniProt?

Yes, you can run BLAST sequence alignment and enrichment analysis against Ensembl and UniProt, as the runtime supports BLAST, BLAT, MUSCLE, DIAMOND, and Enrichr queries for sequence matching and functional enrichment workflows.

Does this gene search approach work with cancer datasets like cBioPortal and COSMIC?

This gene search approach works with cancer datasets like cBioPortal and COSMIC, allowing you to query cancer mutations, explore viral datasets, and retrieve disease associations directly from those specialized bioinformatics databases.

Do I need pandas installed to save sequence and expression query results?

Yes, you need pandas installed to save sequence and expression query results, because the skill uses pandas-backed scripts for reading input data and writing tabular outputs like CSV files for downstream bioinformatics workflows.