What problem does it solve? Building Clinical Decision Support Systems (CDSS) that integrate into EMR workflows is high-stakes work where a single missed drug interaction or unvalidated dose is a patient safety event. This Skill provides tested patterns for implementing safety-critical clinical checks as pure, fully testable functions. ## Core Features & Use Cases - Drug Interaction Checking: Check a new drug against current medications and allergy lists, returning severity-sorted alerts with bidirectional interaction pair detection. - Dose Validation: Validate prescribed doses against weight-based, age-adjusted, renal-adjusted, and absolute maximum rules, blocking (not passing) when required data like patient weight is missing. - Clinical Scoring: Calculate NEWS2 scores from vital signs with risk levels and escalation guidance matching the Royal College of Physicians specification. - Use Case: When a physician enters a warfarin order for a patient already taking aspirin, the interaction checker returns a critical alert that blocks the action in the EMR UI until the clinician documents an override reason in the audit trail. ## Quick Start Implement a drug interaction check that validates warfarin against a patient's current medications and allergy list, returning severity-sorted alerts.