Map legacy gene symbols and aliases to canonical HGNC identifiers.
npx skills add https://github.com/bigbio/hvantk --skill hvantk-resource-hgnc
Please help me install this Agent Skill. Skill: hvantk:resource-hgnc Source: https://github.com/bigbio/hvantk/tree/main/hvantk/skills/hgnc Command: npx skills add https://github.com/bigbio/hvantk --skill hvantk-resource-hgnc
This Skill resolves the ambiguity of human gene nomenclature by providing a standardized, authoritative mapping between gene symbols, HGNC IDs, and various cross-references like Ensembl and UniProt.
Use the hgnc skill to resolve the current approved gene symbol for the legacy identifier BRCA1-A.
High-intent search queries and answers about installing and using this skill.
You can resolve legacy gene symbols and aliases to current approved HGNC identifiers by using this Skill's standardized lookup based on the HGNC complete-set data. It instantly maps outdated or alternative names to their canonical HGNC ID for consistent downstream analysis.
To map Ensembl IDs to HGNC IDs for multi-omics integration, this Skill uses the HGNC ID as a canonical hub for cross-resource mapping. It facilitates joining disparate omics datasets by linking Ensembl, Entrez, and UniProt identifiers to standardized gene nomenclature.
Yes, you can perform large-scale variant annotation using Hail Tables with HGNC data. This Skill implements high-performance Hail Table operations to support massive genomic datasets, enabling efficient cross-reference mapping and standardized nomenclature lookup.
Yes, you need Hail installed along with requests and click, as these are the required dependencies. The Skill implements high-performance Hail Table operations to execute the authoritative HGNC lookup and cross-reference mapping functions.
Variant annotation fails with legacy symbols due to nomenclature ambiguity across heterogeneous omics datasets. This Skill resolves the ambiguity by providing an authoritative mapping that normalizes legacy symbols, aliases, and various cross-references to a single canonical HGNC identifier.
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