What problem does it solve? Researchers often struggle to systematically develop competing, testable explanations for observed phenomena and to structure them into rigorous, publication-ready documents. This Skill guides the full hypothesis generation workflow, from literature synthesis to falsifiable predictions, and produces a professionally formatted LaTeX report. ## Core Features & Use Cases - Competing Hypothesis Development: Generates 3-5 distinct mechanistic hypotheses evaluated against quality criteria like testability, falsifiability, parsimony, and explanatory power. - Experimental Design Planning: Proposes concrete experiments with controls, sample sizes, and statistical approaches drawn from established design patterns (RCTs, cohort studies, in vitro assays, computational models). - Structured LaTeX Reports: Produces a concise 4-page main text with colored hypothesis boxes plus comprehensive appendices, targeting 50+ citations, compiled with XeLaTeX. - Use Case: A biologist observes an unexpected drug response pattern and uses this Skill to search PubMed, formulate four competing mechanistic hypotheses, design discriminating experiments, and deliver a formatted hypothesis report with figures. ## Quick Start Generate competing testable hypotheses with experimental designs and a formatted report for my observation that protein X expression correlates with treatment resistance.
