hypothesis-generation

Structure 3-5 mechanistic hypotheses with evidence, assumptions, and testable predictions.

7|Updated Jan 27, 2026
One-click install
npx skills add https://github.com/wsxwj123/opencode-skills-backup --skill hypothesis-generation-wsxwj123
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: hypothesis-generation
Source: https://github.com/wsxwj123/opencode-skills-backup/tree/main/hypothesis-generation
Command: npx skills add https://github.com/wsxwj123/opencode-skills-backup --skill hypothesis-generation-wsxwj123

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) and assets (resource) components.

What problem does it solve?

Hypothesis-generation helps researchers transform raw observations and data into structured, testable hypotheses, enabling rigorous scientific inquiry and efficient experimental planning.

Core Features & Use Cases

  • Structured workflow to formulate 3-5 competing hypotheses with mechanistic explanations, key evidence, and explicit assumptions.
  • Guidance for literature synthesis, evidence gathering, and transparent evaluation using published quality criteria.
  • End-to-end reporting flow including predictions, discriminating experiments, and well-organized appendices.

Quick Start

Provide three competing mechanistic hypotheses with concise summaries and 2–3 evidence bullets, plus testable predictions and a short justification for each.

Frequently Asked Questions about hypothesis-generation

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I generate testable hypotheses from observational data and experimental findings?

To generate testable hypotheses from observational data, you identify and structure 3-5 mechanistic hypotheses with precise evidence, core assumptions, and testable predictions. This process transforms raw observations into structured formats for rigorous scientific inquiry and experimental planning.

What is a mechanistic hypothesis and how does it differ from a standard prediction?

A mechanistic hypothesis explains the underlying biological or physical mechanisms driving an observation, rather than just predicting an outcome. This approach requires you to provide concise summaries, 2-3 evidence bullets, explicit assumptions, and discriminating experiments to validate the proposed mechanism.

How do I structure competing hypotheses for literature review and evidence synthesis?

You structure competing hypotheses by formulating 3-5 alternatives with mechanistic explanations, key evidence, and transparent evaluation using published quality criteria. The output includes structured appendices formatted for direct integration with hypothesis reporting templates and literature citation practices.

Can I use this hypothesis generation workflow for experimental design planning?

Yes, you can use this workflow for experimental design planning because it generates testable predictions and proposes discriminating experiments for each hypothesis. This end-to-end reporting flow ensures your experimental design directly targets the core assumptions and mechanisms identified during evidence synthesis.

What is the best way to turn raw observations into structured scientific hypotheses?

The best way to turn raw observations into structured scientific hypotheses is to follow a structured workflow that identifies mechanisms, evaluates evidence using quality criteria, and generates testable predictions. This ensures rigorous scientific inquiry through transparent evaluation and organized appendices.

Do I need existing literature citations to start formulating scientific hypotheses?

You do not need existing literature citations to begin, but providing observational data or experimental findings helps. The workflow guides literature synthesis and evidence gathering to formulate 3-5 competing hypotheses with precise evidence, core assumptions, and testable predictions.