kdigo-aki-staging

Calculate KDIGO AKI stages from creatinine and urine output time-series data.

40|17|Updated Oct 27, 2025
One-click install
npx skills add https://github.com/hannesill/m4 --skill kdigo-aki-staging
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: kdigo-aki-staging
Source: https://github.com/hannesill/m4/tree/main/src/m4/skills/clinical/kdigo-aki-staging
Command: npx skills add https://github.com/hannesill/m4 --skill kdigo-aki-staging

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) components.

What problem does it solve?

KDIGO AKI staging requires integrating creatinine changes and urine output to consistently identify and grade AKI in ICU patients, enabling standardized research and monitoring.

Core Features & Use Cases

  • Time-series AKI staging: computes AKI stage at each creatinine/urine output measurement.
  • Baseline-aware: uses the lowest creatinine in the past 7 days to define baseline.
  • Multi-criteria integration: combines creatinine-based and urine output-based criteria, plus CRRT flag for advanced cases.
  • Research-ready outputs: produces per-charttime stages and a smoothed 6-hour window aki_stage_smoothed for stability.
  • Use Case: nephrology research, AKI outcome studies, and ICU renal function monitoring.

Quick Start

Load patient creatinine and urine output data to compute KDIGO AKI stages across time.

Frequently Asked Questions about kdigo-aki-staging

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I calculate KDIGO AKI stages from creatinine and urine output in ICU patients?

To calculate KDIGO AKI stages, this Skill processes time-series ICU data by defining baseline creatinine as the lowest value in the past 7 days, computing 48-hour acute changes, applying urine-output thresholds, and incorporating CRRT status to assign a stage.

What is the best way to define baseline creatinine for KDIGO AKI staging in time-series data?

For KDIGO AKI staging, baseline creatinine is defined as the lowest creatinine value recorded in the past 7 days. This baseline-aware approach ensures accurate detection of acute kidney injury changes over time.

How does KDIGO AKI staging integrate urine output and CRRT status?

KDIGO AKI staging integrates urine output by applying specific volume thresholds over time, while also incorporating a CRRT flag for advanced cases, combining these multi-criteria with creatinine changes to determine the final stage.

Can I use this KDIGO AKI staging Skill for nephrology research and ICU renal monitoring?

Yes, this Skill is designed for nephrology research, renal outcome studies, and ICU renal function monitoring, producing research-ready per-charttime stages and a smoothed 6-hour window stage for stability.

Why use a smoothed 6-hour window for AKI stage calculations in ICU time-series data?

A smoothed 6-hour window, producing the aki_stage_smoothed output, is used to stabilize AKI stage calculations in ICU time-series data, preventing rapid fluctuation between stages due to transient creatinine or urine output spikes.

Does KDIGO AKI staging require 48-hour acute creatinine change calculations?

Yes, KDIGO AKI staging requires computing 48-hour acute creatinine changes relative to the 7-day baseline. This acute change calculation is essential for accurately identifying and grading AKI stages in ICU patients.