kegg-database

Query KEGG pathways, genes, compounds, and drugs via the REST API.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill kegg-database-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: kegg-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/kegg-database
Command: npx skills add https://github.com/yf8578/clawomics --skill kegg-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides direct access to the KEGG database, enabling users to query biological pathways, gene-pathway mappings, metabolic networks, and drug interactions programmatically.

Core Features & Use Cases

  • Pathway Analysis: Retrieve detailed information about metabolic, genetic, cellular, and disease pathways.
  • Gene/Compound Mapping: Map genes to pathways, compounds to reactions, and convert IDs between KEGG and external databases (e.g., UniProt, NCBI).
  • Drug Interaction Data: Query drug-drug interactions.
  • Use Case: Analyze a list of human genes to identify all associated KEGG pathways, then retrieve the specific pathway maps and gene lists for further enrichment analysis.

Quick Start

Use the kegg-database skill to find all human pathways associated with the gene TP53.

Frequently Asked Questions about kegg-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I map a list of genes to KEGG biological pathways programmatically?

To map genes to KEGG biological pathways, this Skill queries the KEGG REST API to retrieve gene-pathway mappings across multiple organisms. It takes gene lists as input and returns associated metabolic, genetic, and cellular pathway information for bioinformatics workflows.

Can I convert biological IDs between KEGG and external databases like NCBI?

Yes, you can convert biological IDs between KEGG and external databases like NCBI or UniProt. This Skill utilizes the KEGG REST API to perform ID conversion, translating gene and compound identifiers across supported external databases for academic research.

What is the best way to retrieve drug interaction data from the KEGG database?

The best way to retrieve drug interaction data from the KEGG database is by using this Skill to query the KEGG REST API. It programmatically accesses drug information, enabling users to extract specific drug-drug interaction data for pharmacological research.

Does the KEGG REST API access method support querying metabolic pathways for specific organisms?

Yes, the KEGG REST API access method supports querying metabolic pathways for specific organisms. This Skill retrieves detailed information about metabolic networks, disease pathways, and enzyme data across various organisms for biological pathway analysis.

How do I get detailed compound and reaction information for pathway analysis using Python?

To get detailed compound and reaction information for pathway analysis, this Skill uses Python scripts to interact with the KEGG REST API. It queries compound data and maps compounds to their corresponding reactions within metabolic pathways.

Are there limitations to using the KEGG REST API for high-throughput genomic data retrieval?

When using the KEGG REST API for high-throughput genomic data retrieval, limitations include potential rate limits and response times inherent to direct database querying. This Skill handles interactions via Python scripts but does not bypass external API constraints.