lethal-variance-detection

Detect drugs with lethal safety variance across species before dosing guidance.

27|6|Updated Mar 17, 2026
One-click install
npx skills add https://github.com/OpenVet-Projects/VetClaw --skill lethal-variance-detection
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: lethal-variance-detection
Source: https://github.com/OpenVet-Projects/VetClaw/tree/main/skills/safety/lethal-variance-detection
Command: npx skills add https://github.com/OpenVet-Projects/VetClaw --skill lethal-variance-detection

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Detect drugs and substances with extreme safety variance across species where a safe dose in one species is lethal in another. This is a critical safety consideration to prevent iatrogenic harm.

Core Features & Use Cases

  • Cross-species risk flagging: Automatically identify drugs with lethal variance across species and surface warnings before dosing advice.
  • Dosing guidance gating: Require explicit species checks and caution when applying dosing information to non-target species.
  • Use Case: A veterinarian evaluating acetaminophen for a multi-species household is warned that it is lethal in cats before any dosage is suggested.

Quick Start

When assessing a drug for a given patient, run this skill first to confirm species-specific safety.

Frequently Asked Questions about lethal-variance-detection

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I check veterinary drug safety for cross-species lethal variance?

Cross-species lethal variance detection identifies drugs where a safe dose in one species is lethal in another. It enforces explicit species checks and surfaces safety warnings before providing any veterinary dosing guidance.

What is lethal variance detection in veterinary toxicology?

Lethal variance detection in veterinary toxicology flags drugs with extreme safety variance across species to prevent iatrogenic harm. It automatically identifies substances where cross-species dosing errors could be fatal before recommendations are made.

How do I prevent unsafe species-specific dosing errors in multi-species households?

To prevent unsafe species-specific dosing errors, run a cross-species safety check first to confirm species-specific safety. The system gates dosing guidance, requiring explicit species checks and safe alternatives before suggesting any dosage.

Does cross-species drug safety checking apply to multi-species veterinary cases?

Yes, cross-species drug safety checking applies to both single- and multi-species veterinary cases involving dogs, cats, and horses. It automatically flags lethal variance and surfaces warnings before any dosing information is provided.

When should I run a cross-species safety alert before giving dosing guidance?

You should run a cross-species safety alert before any drug recommendation or dosing decision in veterinary practice. It serves as a critical pre-dosing check to identify lethal variance and require safe, species-appropriate alternatives first.

What are the limitations of relying on standard veterinary dosing without species checks?

Standard veterinary dosing without explicit species checks risks iatrogenic harm from lethal variance, where a safe dose in one species is fatal in another. Cross-species safety gating is required to surface warnings and safe alternatives before dosing.