MCP BioMCP

Query gene, variant, literature, and clinical trial data from NCBI, PubMed, and ClinicalTrials.gov.

2|Updated Mar 10, 2026
One-click install
npx skills add https://github.com/caoronglin/copaw-skills --skill mcp-biomcp
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: MCP BioMCP
Source: https://github.com/caoronglin/copaw-skills/tree/main/skills/mcp-biomcp
Command: npx skills add https://github.com/caoronglin/copaw-skills --skill mcp-biomcp

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill streamlines complex bioinformatics tasks by integrating multiple specialized tools for gene, protein, and clinical trial analysis, eliminating the need to navigate disparate databases and interfaces.

Core Features & Use Cases

  • Gene Information: Query detailed information about genes using NCBI Gene and MyGene.info.
  • Variant Analysis: Analyze genetic variations and their clinical significance with ClinVar and gnomAD.
  • Literature Search: Find relevant biomedical research papers through PubMed.
  • Clinical Trials: Search for ongoing and completed clinical trials.
  • Use Case: A researcher needs to understand the clinical significance of a specific gene mutation. They can use this Skill to query gene information, check for known variants in ClinVar, and find related research papers on PubMed, all within a single interaction.

Quick Start

Use the BioMCP skill to search for information about the TP53 gene.

Frequently Asked Questions about MCP BioMCP

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I search for gene information and related PubMed literature in one place?

You can search for gene information and PubMed literature in one place by querying NCBI Gene and MyGene.info simultaneously. This consolidates biomedical research papers and detailed gene data into a single interaction, eliminating the need to navigate disparate databases.

What is the best way to analyze genetic variations and their clinical significance?

To analyze genetic variations and their clinical significance, query ClinVar and gnomAD. This approach provides variant analysis directly, allowing researchers to understand the clinical impact of specific gene mutations without switching interfaces.

Can I find ongoing and completed clinical trials using a gene mutation?

Yes, you can find ongoing and completed clinical trials using a gene mutation by searching ClinicalTrials.gov data. This integrates clinical trial retrieval with genomics and molecular biology research within a single bioinformatics analysis workflow.

Does this bioinformatics toolkit require external dependencies or API keys?

This bioinformatics toolkit requires no external dependencies. It provides comprehensive bioinformatics analysis by integrating robust data parsing and direct API interaction capabilities for accurate information retrieval from authoritative sources like NCBI and PubMed.

How do I query detailed information about a specific gene like TP53?

To query detailed information about a specific gene like TP53, use the integrated bioinformatics toolkit to access NCBI Gene and MyGene.info. This retrieves comprehensive gene data directly, supporting fields such as genomics and molecular biology.