molclaw-equiscore-tool

Official

Fast end-to-end pocket extraction and scoring

AuthorInternScience
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Automates the extraction of binding pockets from docking outputs and the scoring/ranking of ligand-pocket pairs so researchers can convert docking results into prioritized candidate lists without manual preprocessing.

Core Features & Use Cases

  • Pocket extraction: Split docking-result SDFs into single-molecule SDFs and generate pocket folders ready for screening.
  • EquiScore screening: Batch GPU-enabled scoring that produces per-pocket CSV predictions and summary statistics for ranking and enrichment-style filtering.
  • End-to-end pipeline: One-click workflow that runs pocket extraction then screening and returns organized run directories, making it suitable for virtual screening, hit prioritization, and downstream validation workflows.

Quick Start

Run the EquiScore pipeline on a docking-result SDF and receptor PDB to obtain a ranked prediction CSV and organized run directory.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: molclaw-equiscore-tool
Download link: https://github.com/InternScience/MolClaw/archive/main.zip#molclaw-equiscore-tool

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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