Molecular Networking with matchms

Official

Build MS/MS molecular networks with matchms.

AuthorHolobiomicsLab
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Molecular networking analysis of MS/MS data often requires coordinating multiple tools and pipelines; this skill provides a coherent guide using the matchms library to load spectra, compute similarities, and build networks in Python.

Core Features & Use Cases

  • Load MS/MS data in formats supported by matchms (MGF, mzML, mzXML, MSP, JSON) and compute spectral similarities with cosine-based and Modified Cosine metrics to build molecular networks.
  • Create networks that reveal molecular families, support dereplication, and facilitate annotation; suitable for metabolomics, cheminformatics, and natural product discovery.
  • Integrate with GNPS and Cytoscape workflows for visualization and downstream analysis.

Quick Start

Install and run a basic molecular networking workflow using matchms to process a small MS/MS dataset.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: Molecular Networking with matchms
Download link: https://github.com/HolobiomicsLab/Toolomics/archive/main.zip#molecular-networking-with-matchms

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
View Source Repository

Agent Skills Search Helper

Install a tiny helper to your Agent, search and equip skill from 471,000+ vetted skills library on demand.