ms-format-conversion

Community

Convert vendor mass-spec files to open formats

Authordailycafi
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Mass spectrometry instruments produce proprietary vendor files that block downstream analysis and sharing; this Skill provides reliable, reproducible conversion to open formats (mzML, mzXML) and tools to validate converted data for metabolomics pipelines.

Core Features & Use Cases

  • Vendor-to-open conversion: msConvert (ProteoWizard) guidance and Docker usage to convert Thermo RAW, AB SCIEX WIFF, Agilent .d, Waters .raw, and Bruker formats to mzML or mzXML.
  • Preprocessing choices: Centroiding (vendor-native or algorithmic), encoding precision selection (32/64-bit), and selective filtering (msLevel, rt window, m/z window).
  • Batch processing & validation: Example bash and Python batch scripts, pyopenms-based interconversion and validation routines to check centroid/profile status, spectrum counts, and RT ranges.

Quick Start

Convert all Thermo RAW files in /data/raw to centroided mzML files in /data/mzml using msConvert with vendor peak-picking (or run the provided Docker msConvert image on non-Windows systems).

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

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Please help me install this Skill:
Name: ms-format-conversion
Download link: https://github.com/dailycafi/metabolism-skills/archive/main.zip#ms-format-conversion

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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