multi-omics-integration
CommunityLayer multiple ENCODE data types for comprehensive analysis.
Authorammawla
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Integrates diverse ENCODE genomic datasets to build a unified view of gene regulation and chromatin dynamics.
Core Features & Use Cases
- Data Integration: Combines RNA-seq, ATAC-seq, histone modifications, TF ChIP-seq, and 3D genome data for tissue-specific regulatory landscapes.
- Analytical Frameworks: Applies chromatin state segmentation, enhancer-gene linking, and regulatory network inference.
- Use Case: A researcher studying pancreatic islet cells integrates accessible chromatin, histone marks, gene expression, and Hi-C data to elucidate cell type-specific regulatory circuits.
Quick Start
Align and analyze ENCODE datasets across multiple modalities to identify active enhancers and their target genes in your tissue of interest.
Dependency Matrix
Required Modules
ChromHMMbedtoolsHiC-ProGREATEnformerscVISeuratLIGERMOFA+
Components
scriptsreferencesassets
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: multi-omics-integration Download link: https://github.com/ammawla/encode-toolkit/archive/main.zip#multi-omics-integration Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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