neuropixels-analysis

Automate Neuropixels spike sorting and curation by running a modular workflow that preprocesses raw data, applies motion correction, sorts spikes, computes quality metrics, and exports curated units to Phy.

Drift correction in extracellular probe data is handled during preprocessing using SpikeInterface, which applies motion correction algorithms before spike sorting to stabilize recording quality across sessions.

Yes, SpikeInterface supports both NP1.0 and NP2.0 probe configurations, processing raw recordings through standardized workflows that integrate probeinterface for accurate channel mapping and data loading.

Compute quality metrics for sorted spike units during post-processing using SpikeInterface, which calculates standardized metrics based on Allen and IBL standards to facilitate automated and AI-assisted curation.

Yes, you can export sorted spike data to Phy for manual curation, enabling efficient visual review of automated quality assessments and AI-assisted curation results generated by the pipeline.

Probeinterface is required for Neuropixels data preprocessing to define accurate channel geometry and probe layouts, ensuring correct spatial referencing during motion correction and spike sorting steps.