novelty-gap-mapper

Classify research gaps using a six-axis framework and generate weighted novelty scores.

Updated Jan 18, 2026
One-click install
npx skills add https://github.com/tito-gh/healthcare --skill novelty-gap-mapper
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: novelty-gap-mapper
Source: https://github.com/tito-gh/healthcare/tree/main/.claude/skills/novelty-gap-mapper
Command: npx skills add https://github.com/tito-gh/healthcare --skill novelty-gap-mapper

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

This skill helps researchers systematically identify and classify gaps between existing evidence and a target drug/indication, enabling prioritization of high-value research opportunities.

Core Features & Use Cases

  • Six-axis gap classification across Population, Intervention, Comparator, Outcome, Time, and Setting to capture unaddressed areas.
  • Multi-criteria novelty scoring with a weighted formula to rank opportunities.
  • EHR-RWD leverage for data-driven differentiation and timing advantages.
  • Gap × feasibility matrix to guide prioritization and resourcing.
  • Output formats aligned with the Novelty Gap Analysis template (summary, detailed gaps, and recommended actions).

Quick Start

Provide the evidence report path, DRUG, and INDICATION, and run the skill to generate the novelty-gap analysis.

Frequently Asked Questions about novelty-gap-mapper

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I identify clinical research gaps for a target drug indication?

To identify clinical research gaps, compare existing evidence reports against a target drug and indication using a six-axis framework covering Population, Intervention, Comparator, Outcome, Time, and Setting. This systematically classifies unaddressed areas to reveal high-value opportunities.

What is the best way to quantify novelty for research gap prioritization?

Quantifying research gap novelty involves applying a multi-criteria weighted scoring formula to each identified gap. This generates a quantified novelty score per gap and an overall score, allowing you to rank and prioritize research opportunities objectively.

How does EHR and real-world data factor into research gap mapping?

EHR and real-world data (RWD) factor into research gap mapping by identifying data-driven differentiation and timing advantages. Leveraging the company's EHR-RWD strengths helps assess feasibility and guides the resourcing of prioritized clinical research opportunities.

Can I use evidence reports to generate a structured novelty gap analysis?

Yes, you can generate a structured novelty gap analysis by providing an evidence report path alongside the target drug and indication. The analysis outputs a gap summary, detailed classification, and recommended actions based on a standardized template.

How do I map unaddressed clinical evidence areas to actionable opportunities?

Mapping unaddressed clinical evidence areas to actionable opportunities is done by plotting identified gaps against a feasibility matrix. This guides prioritization and resourcing by highlighting where your EHR-RWD strengths align with high novelty scores.

Limitations of using a six-axis framework for research gap classification?

The six-axis framework for research gap classification is limited to Population, Intervention, Comparator, Outcome, Time, and Setting. It requires existing evidence reports and company EHR-RWD data inputs to function, meaning gaps outside these axes or data sources remain unclassified.